Actor Anupam Kher has completed the shooting of his 500th film 'The Big Sick'. He gave this information via tweet. Anupam Tweet, 'Finished shooting of my 500th film The Big Sick in NY. It was a pleasure to be part of this LANDMARK film.' Anupam thanked producers to be part of this film. Holly Hunter, Zoe Kazan, Kumail Nanjiani, Ray Romano were there with Anupam Kher in this film. In an another tweet he wrote, 'Thank you my producers Judd Apatow & Barry Mendel for making me part of The Big Sick. It has been a pleasure.' According to report, 'A Big Sick is a story of Couple, who for taking their relation forward and Face many difficulties due to differences in cultures.'